Continuous glucose monitoring for glycaemic control and cardiovascular risk reduction in patients with type 2 diabetes not on insulin therapy

Topics: Type 2 Diabetes, Cardiovascular Outcomes, Behavior Change

Key question: What are the potential benefits of widening the application of glucose sensors in type 2 diabetes?

Research Spotlight: “Continuous glucose monitoring for glycaemic control and cardiovascular risk reduction in patients with type 2 diabetes not on insulin therapy: A clinical trial” Reed J, et al. Diabetes Obes Metab. 2024; 26(7): 2881-2889.

Background: Glucose sensor device uptake among people with type 2 diabetes has been slower despite increasing evidence.

Main outcomes of the study:

Glucose sensor use was associated with a ~8% reduction in the absolute 10-year predicted risk|| for ASCVD (P=0.03).
Glucose sensor use was associated with a reduction in average glucose (184.0 to 147.2 mg/dl, p < .001), an increase in time in range (57.8 to 82.8%, p < .001) and a trend towards lower glucose variability (26.2 to 23.8%).
Glucose sensor use was associated with significant reductions in HbA1c, BMI, triglycerides, blood pressure, total cholesterol, and diabetes distress.
Glucose sensors may be a useful tool to optimize current and newly introduced medications.

Key takeaways for healthcare providers:

Glucose sensor use was associated with improved glycaemic control and cardiometabolic risk in patients with type 2 diabetes who were not on insulin.
A glucose biosensor may serve as a behavioral modification tool to improve the management of diabetes.

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Continuous glucose monitoring for glycaemic control and cardiovascular risk reduction in patients with type 2 diabetes not on insulin therapy

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